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Image Search Results
Journal: Nature medicine
Article Title: Niclosamide ethanolamine improves blood glycemic control and reduces hepatic steatosis in mice
doi: 10.1038/nm.3699
Figure Lengend Snippet: Oral NEN improves glycemic control in db/db mice. ( a ) Fasting blood glucose concentration of db/db mice fed with either normal chow diet (control), or the same chow diet containing 1,500 ppm NEN (NEN), measured at indicated time points. ( b ) Basal plasma insulin concentration of the db/db mice as defined in a , measured at indicated time points. ( c ) Glycated hemoglobin A1c (HbA1c) level of the db/db mice as defined in a , measured at day 60. ( d ) Body weight of the db/db mice as defined in a , measured at indicated time points. ( e ) Daily food intake of the db/db mice as defined in a . n = 9 for all groups. Student t-test; * P < 0.05; *** P < 0.001; error bar, s.d.
Article Snippet: Consistently, the glycated
Techniques: Control, Concentration Assay, Clinical Proteomics
Journal:
Article Title: Effects of peroxisome proliferator-activated receptor-? and -? agonist, JTT-501, on diabetic complications in Zucker diabetic fatty rats
doi: 10.1038/sj.bjp.0703328
Figure Lengend Snippet: Effects of JTT-501 and troglitazone on blood biochemical parameters in ZDF rats. Blood samples were taken from tail vein weekly. Serum insulin (A), serum glucose (B), blood HbA1c (C), serum triglyceride (D), and serum cholesterol (E) were measured as described in Methods. Each point represents the mean±s.e.mean (n=8). ¶P<0.05, ¶¶P<0.01 vs lean (Student's t-test). *P<0.05, **P<0.01 vs ZDF control (ANOVA followed by Dunnett's test). †P<0.05, ††P<0.01 vs ZDF control (Student's t-test).
Article Snippet: Kits for the measurement of metabolites, hormones, ions, and other substances were purchased as follows: glucose, triglyceride, cholesterol, N-acetylglucosaminidase (NAG), creatinine from Boehringer Mannheim (Tokyo, Japan); insulin radioimmunoassay (RIA) from Shionogi (Tokyo, Japan); rat insulin from Linco Research (St. Charles, MO, U.S.A.),
Techniques: